The main mechanism of action of albendazole – its inhibitory effect on beta-tubulinapolimerizatsiyu, which leads to the destruction of cytoplasmic microtubules trenbolone acetate 100mg of cells of the intestinal tract of worms; change the course of biochemical processes (inhibits glucose utilization), blocks the movement of secretory granules, and others. organelles in muscle cells of roundworms, causing their death. The most effective impact on the larval forms of cestodes – Echinococcus granulosus and Taenia solium, hookworms – Strongyloides stercolatis.
Albendazole sulfoxide in the liver is converted into albendazole sulfone (secondary metabolite) and other oxygenated products. T1 / 2 albendazole sulfoxide -. 8.12 hours Return to form various metabolites in urine.
Renal excretion of albendazole and its primary metabolite, albendazole sulfoxide, a small, ground clearance is not changed in patients with impaired renal function.
Against the background of liver disease – increased bioavailability, C max albendazole sulfoxide increased by 2 times, T1 / 2 longer. Albendazole is an trenbolone acetate cycle inducer of microsomal enzymes of the cytochrome P-450; It accelerates the metabolism of many drugs.
Indications for use:
Nematodes (ascariasis, enterobiosis, hookworm, necatoriasis, trichocephalosis et al.). Mixed worm infestation.
Strogiloidoz, neurocysticercosis, caused by the larval form of the pork tapeworm (Taenia solium); hydatid disease of the liver, lung, peritoneum, caused by the larval form of the dog tapeworm (Echinococcus granulosus). As an adjunct to surgical treatment of cysts ehinokokkoznyh.
Giardiasis and trenbolone acetate 100mg toxocariasis.
Individual intolerance (including to other benzimidazole derivatives), the retina of the eye, and pregnancy.
The caution used in violation of hematopoiesis, hepatic dysfunction (before and during treatment regularly check its function), breastfeeding.
Dosage and administration:
The drug is taken orally, during a meal. It is recommended that simultaneous treatment of all family members. Standard dosage in the treatment of roundworm infestation for adults and children over 2 years old – 400 mg or 20 ml of the suspension into single dose; and echinococcosis neurocysticercosis: patients with a body weight of 60 kg or more – 400 mg 2 times a day, less than 60 kg – 15 mg / kg per day in 2 divided doses; maximum daily dose – 800 mg * (2 400 mg tablets). The course of treatment with neurocysticercosis – 8-30 days, echinococcosis – 3 cycles of 28 days with a 14 day break between cycles.When giardiasis in children – 10-15 mg / kg once a day for 5-7 days. When toxocarosis – adults and children over 14 years weighing more than 60 kg – 400 mg 2 times a day 7-14 days, less than 60 kg – 200 mg 2 times a day 7-14 days. Babies – 10 mg / kg two times a day 7-14 days.
Dexamethasone and cimetidine increase albendazole sulfoxide concentrations in the blood.
In trenbolone acetate 100mg women of childbearing age before treatment is carried out in the absence of pregnancy test. During therapy required reliable contraception.
Patients neurocysticercosis should receive appropriate therapy with steroids, and anticonvulsants. Oral or intravenous corticosteroids are used to prevent hypertensive attack antitsistovoy the first week of therapy.
Recommended blood cell composition control; in the event of leukopenia suspend therapy.
Blood tests should be carried out at the beginning of each 28 day cycle, and every 2 weeks during therapy Albendazole. Continue treatment Albendazole may decrease if the total white blood cells and leukocytes neyrotrofilnyh moderate and does not progress. Running low dose t3 clen cycle trying to lose bodyfat isn’t a real hot idea imo.
Trenbolone acetate is an injectable anabolic steroid of a non-genomic effect with moderate androgenic activity, used to build muscle mass, increase strength and endurance. Has a powerful effect, while it is considered relatively safe. In particular, it is not susceptible to aromatase, but it can exhibit estrogenic and progestagenic activity in large dosages and prolonged trenbolone acetate 100mg continuous use.From other steroids of similar action, acetate is characterized by the altered structure of the rings B and C, characteristics, principle and effect of the action.
There is still no consensus and confirmation of whether Trenbolone acetate affects progestagen receptors. In some cases, this effect is recorded, in others it does not. Whatever it was, the drug is not deprived of estrogen and progestagenic activity completely. It is one of the most effective among the currently available steroids and at the same time one of the safest. Even testosterone and Nandroln are inferior to it in terms of the duration of action on androgen receptors.